Piedmont Newnan Hospital is located on approximately 114 acres near Interstate 85 in Newnan, Georgia. The 365,000 square foot, 9-floor, 136-bed hospital facility improves patient access and wayfinding; provides flexibility for changing clinical, technology and community needs; increases operational efficiencies and accommodates future growth. Private, inpatient rooms are adaptable to varying acuity needs of patients and include 14 post-partum beds, 18 critical care beds and 104 general medical/surgical patient beds. The facility features eight operating rooms and 23 patient rooms in the emergency department.

The hospital also employs sustainable building strategies such as energy efficiencies and water reuse and conservation technologies
reducing future operating costs, providing a healthier work environment and reducing the overall environmental impact of the project. It has been designed to comply with the Leadership in Energy and Environmental Design (LEED) Green Building Rating System™.

Designated green spaces and natural areas serve to organize the overall campus and provide restorative spaces for patients, visitors and staff. These "green belts" are used to facilitate wayfinding, extending from public parking to the lobby and along the public mall. The public mall simplifies access to many of the clinical services and destinations for patients and visitors such as radiology, laboratory, cardiopulmonary and respiratory therapy services.